Every year, scientists undertake some truly baffling experiments, and 2021 was no exception. From growing mini-brains with their own eyes in petri dishes to reanimating 24,000-year-old self-replicating zombies from the Siberian permafrost, here are the absolute weirdest scientific experiments of the year.
Growing miniature human brains with their own eyes
In August, a group of scientists made news that was equal parts fascinating and horrifying when they announced they had successfully lab-grown a tiny human brain with its own pair of eyes. They made the Cronenberg-esque mini brain, called an organoid, by transforming stem cells into neural tissue, then stimulating the cells with chemical signals to form tiny rudimentary “optic cups” filled with light-sensitive cells.
Thankfully for our collective sanity and for the mini-brains themselves, the tiny organoids don’t have nearly enough neural density to be conscious — so they won’t be asking themselves anytime soon how they awakened as a lost pair of eyes sliding around a petri dish. They are, however, incredibly useful constructs for studying brain development and potentially creating cures for retinal disorders that cause blindness — something that the researchers want to study.
Read more: Lab-made mini brains grow their own sets of ‘eyes’
Finding that crows understand the concept of zero
If the Cronenburg body-horror of the last entry didn’t move you, this year also saw scientists reveal an experiment more in line with Hitchcock’s classic horror film “The Birds” — proving that crows were smart enough to understand the concept of zero. The concept of zero, ostensibly developed by human societies somewhere in the fifth century A.D., requires abstract thinking. So it came as quite a surprise when a June paper in The Journal of Neuroscience revealed that crows not only picked zero as distinct from other numbers, but also associated it more readily with the number one than with higher numbers.
Scans of the birds’ brain activity during the experiments showed that crows have specially tuned neurons for understanding the null number, but what they use those brain cells for (besides potentially plotting to take over the world, of course) is a mystery. The scientists were amazed that both human and crow brains can compute zero even though we shared our last common ancestor with birds well before the extinction of the dinosaurs; this shows that evolution takes multiple routes to create brains with the same higher-level functions.
Read more: Crows understand the ‘concept of zero’ (despite their bird brains)
Figuring out why brazil nuts rise to the top of the bag
Read more:10 of the weirdest experiments of 2021 – News Concerns